Kris A Steinbrecher Selected Research

uroguanylin

11/2014	Effect of guanylate cyclase-C activity on energy and glucose homeostasis.
9/2013	Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen.
1/2011	Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier.
9/2005	Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse model.

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Kris A Steinbrecher Research Topics

Disease

8	Inflammation (Inflammations) 04/2017 - 02/2008
5	Neoplasms (Cancer) 01/2018 - 09/2005
4	Colitis 01/2020 - 02/2008
4	Adenoma (Adenomas) 06/2014 - 12/2002
3	Carcinogenesis 01/2018 - 01/2011
3	Diarrhea 01/2014 - 12/2002
2	Infections 01/2018 - 09/2013
2	Non-alcoholic Fatty Liver Disease 07/2017 - 05/2014
2	Body Weight (Weight, Body) 04/2017 - 11/2014
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2017 - 05/2013
2	Obesity 11/2014 - 05/2014
2	Colitis-Associated Neoplasms 06/2014 - 04/2010
2	Colonic Neoplasms (Colon Cancer) 06/2014 - 04/2010
2	Constipation 01/2014 - 03/2011
2	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2014 - 03/2011
1	Abscess 01/2020
1	Hypertrophy 01/2020
1	Splenomegaly 01/2018
1	Salmonella Infections (Salmonellosis) 01/2018
1	Shock 01/2017
1	Bacterial Infections (Bacterial Infection) 01/2017
1	Cytokine Release Syndrome 01/2017
1	Glucose Intolerance 11/2014
1	Hypoprothrombinemias (Prothrombin Deficiency) 06/2014
1	Aberrant Crypt Foci 06/2014
1	Hemorrhage 06/2014
1	Fatty Liver 05/2014
1	Abdominal Pain (Pain, Abdominal) 01/2014
1	Ulcerative Colitis 05/2013
1	Hyperplasia 04/2011
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 03/2011
1	Afibrinogenemia (Fibrinogen Deficiency) 04/2010
1	Wounds and Injuries (Trauma) 06/2006
1	Polyps 09/2005
1	Necrosis 06/2003

Drug/Important Bio-Agent (IBA)

8	CytokinesIBA 01/2020 - 01/2013
5	guanylinIBA 09/2013 - 12/2002
4	uroguanylinIBA 11/2014 - 09/2005
4	Guanylate Cyclase (Guanylyl Cyclase)IBA 11/2014 - 03/2011
3	Interleukin-17 (Interleukin 17)IBA 07/2017 - 05/2014
3	sodium sulfate (sodium bisulfate)FDA LinkGeneric 06/2014 - 02/2008
3	Dextrans (Dextran)FDA Link 06/2014 - 02/2008
3	LigandsIBA 01/2014 - 06/2011
2	Peptide Hydrolases (Proteases)FDA Link 01/2020 - 06/2014
2	Transcription Factors (Transcription Factor)IBA 01/2018 - 02/2008
2	Interleukin-6 (Interleukin 6)IBA 01/2017 - 04/2010
2	AzoxymethaneIBA 06/2014 - 04/2010
2	Hemostatics (Antihemorrhagics)IBA 06/2014 - 04/2010
2	InterleukinsIBA 05/2014 - 01/2013
2	heat stable toxin (E coli)IBA 01/2014 - 12/2002
2	Proteins (Proteins, Gene)FDA Link 01/2013 - 04/2010
2	Enterotoxin ReceptorsIBA 01/2011 - 09/2005
2	NF-kappa B (NF-kB)IBA 02/2008 - 06/2003
1	Polymeric Immunoglobulin Receptors (Polymeric Immunoglobulin Receptor)IBA 01/2018
1	CorticosteroneIBA 07/2017
1	Toll-Like Receptor 4IBA 07/2017
1	Phosphotransferases (Kinase)IBA 04/2017
1	prouroguanylinIBA 11/2014
1	Prothrombin (Factor II)IBA 06/2014
1	Thrombin FDA Link 06/2014
1	LipidsIBA 05/2014
1	EnzymesIBA 05/2014
1	NADPH Oxidases (NAD(P)H oxidase)IBA 05/2014
1	NADP (NADPH)IBA 05/2014
1	ChemokinesIBA 09/2013
1	Chemokine CCL11IBA 05/2013
1	Messenger RNA (mRNA)IBA 01/2013
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013
1	Interleukin-13IBA 04/2011
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 04/2011
1	Peptides (Polypeptides)IBA 03/2011
1	estropipate (Ogen)FDA LinkGeneric 04/2010
1	IntegrinsIBA 04/2010
1	Macrophage-1 Antigen (Macrophage 1 Antigen)IBA 04/2010
1	Blood Coagulation Factors (Coagulation Factor)IBA 04/2010
1	FibrinIBA 04/2010
1	Fibrinogen (Factor I)FDA Link 04/2010
1	AnionsIBA 11/2007
1	ChloridesIBA 11/2007
1	Histones (Histone)IBA 06/2006
1	Enterotoxins (Enterotoxin)IBA 09/2005
1	I-kappa B KinaseIBA 06/2003
1	ChromatinIBA 06/2003
1	SecretagoguesIBA 12/2002

Therapy/Procedure

2	Therapeutics 04/2017 - 04/2010
1	Immunotherapy 01/2018